Does Suicide Risk Show Up in the Blood?

Newly identified serum biomarkers have the potential to flag patients, via blood testing, with major depressive disorder (MDD) at high risk of suicide. Investigators found patients with MDD who died by suicide had a gene expression signature in blood distinct from patients with MDDwho died by other means. The signature included genes involved in stress … Read more

Clozapine and Cancer Risk: New Data

Dr. Jari Tiihonen Long-term treatment with clozapine is associated with a small, but significant, risk of hematological malignancies in individuals with schizophrenia, new research shows. Investigators found long-term clozapine use of more than 5 years was linked to a 2.7-fold increased risk of hematological malignancies in a dose-dependent manner compared with other antipsychotics. “Our results … Read more