Time to Test Effects of CBD in Cardiovascular Disease?

Well-designed clinical trials to test the safety and efficacy of cannabidiol (CBD) for cardiovascular disease are needed, based on evidence from preclinical studies showing that it has anti-inflammatory effects, a new report suggests. The systematic review of nine preclinical studies found reproducible positive adverse outcomes in vivo models with CBD. Mechanisms for the findings included … Read more

LAIAs More Effective Than Oral Antipsychotics for Schizophrenia

For patients with schizophrenia, long-acting injectable antipsychotics (LAIAs) are associated with a lower risk than oral antipsychotics (OAs) for disease relapse and hospitalization ― and they carry no increased risk for adverse events, new research shows. Investigators analyzed data for more than 70,000 patients with schizophrenia and found that, compared with OAs, LAIAs were associated … Read more

Metabolic Syndrome Raises Dementia Risk in Under-60s

The more components of metabolic syndrome a person has in midlife seems to raise their risk of dementia, although that relationship seems to go away after age 70, a post hoc analysis of data from a major European cohort study has found. A team of European researchers reported online in the journal Diabetes Care that … Read more

Recent-Onset CV Disease Raises Risk for a Psychiatric Diagnosis

The study covered in this summary was published on MedRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Patients diagnosed with cardiovascular disease (CVD) are at increased risk for a psychiatric diagnosis, independent of family characteristic, comorbidities, and medical history. Development of a psychiatric disorder in the year after a CVD … Read more

Running to the Top: Exercise and Mental Health

An apple a day keeps the doctor away! We’ve probably been given this advice or know of others who have been given this advice time and time again… to eat healthier, and more important, to exercise. While exercise is not necessarily the cure-all for the world’s infections and diseases, it plays an important role in … Read more

TBI Linked to ‘Striking’ Risk for CVD, Endocrine, Brain Disorders

Mild traumatic brain injury (TBI) is linked to a significantly increased risk for a host of subsequent cardiovascular, endocrine, neurologic, and psychiatric disorders, new research shows. Incident of hypertension, coronary heart disease, diabetes, stroke, depression, and dementia all began to increase soon after the brain injury and persisted over a decade in both mild and … Read more

Exercise Provides Twice the CV Benefit in Anxiety, Depression

Meeting guideline-recommended exercise targets is associated with a reduced risk of cardiovascular disease (CVD) in everyone, but the benefits may be particularly clear for people with anxiety and depression, a new analysis suggests. In a study of more than 50,000 adult patients with or without CVD or risk factors who were followed for a median … Read more

New Tool Cuts CVD Risk in Patients With Serious Mental Illness

A clinical decision support (CDS) system that can be implemented in primary care reduces cardiovascular risk factors (CV) common in patients with serious mental illness (SMI), new research suggests. Investigators assessed more than 70 primary care clinics that treated close to 9000 patients with SMI. Disorders included schizophrenia, bipolar disorder, and schizoaffective disorder. The clinics … Read more