Visual Impairment More Common in Minority Youth

Race, ethnicity, and socioeconomic status are closely associated with visual impairments in adolescents in the United States, researchers have found. The study showed that adolescents who identified as Black, Mexican-American, of low-income, or as non-US citizens were two to three times more likely than White adolescents to report vision problems and to perform worse on … Read more

Urgent Need for Research Into Psychedelic Tx for Older Adults

Older age is associated with many health conditions that could potentially benefit from psychedelic-assisted therapy, yet very few older adults have been included in clinical trials of psychedelics, new research shows. “Geriatric psychiatrists and others caring for older adults are interested in how much is known about psychedelic use in older adults,” study investigator C. … Read more

Time to Test Effects of CBD in Cardiovascular Disease?

Well-designed clinical trials to test the safety and efficacy of cannabidiol (CBD) for cardiovascular disease are needed, based on evidence from preclinical studies showing that it has anti-inflammatory effects, a new report suggests. The systematic review of nine preclinical studies found reproducible positive adverse outcomes in vivo models with CBD. Mechanisms for the findings included … Read more

Easing the Trauma of Terminal Illness

Something was gnawing at Manish Agrawal, MD. Every day, the oncologist treated patients with standard cancer therapies, but his care could never touch their deepest pains: their despair about death. “In 20 years, I’ve treated close to 100,000 patients,” Agrawal says, “and the one thing I know we don’t do well is dying.” Hospitalist Shoshana … Read more

Psychedelics May Ease Fear of Death and Dying

Psychedelics can produce positive changes in attitudes about death and dying — and may be a way to help ease anxiety and depression toward the end of life, new research suggests. In a retrospective study of more than 3000 participants, near-death experiences occurred naturally or via participants a psychedelic drug had a “remarkably” similar effect … Read more

Active Shooter Drills May Be Harming Children, but Doctors Offer Help

Gun attacks in classrooms across the nation have led principals and other school leaders to implement “active shooter” drills to try to increase the safety of their students and faculty. The drills can range from staging lockdowns and sheltering in place to quasi dramas with mock shooters roaming the halls. Although the goals of these … Read more

Noninvasive Brain Stimulation May Boost Memory for 4 Weeks

Transcranial alternating current stimulation (tACS) for 20 minutes over 4 consecutive days can improve both short- and long-term memory for at least 1 month in older adults, new research suggests. The effects were “moderate to large and the overwhelming majority of participants, 85% to 90%, experienced the memory benefit,” study investigator Robert Reinhart, PhD, Cognitive … Read more

Postpartum Depression Risk Higher With Family Psych History

Mothers who have a family history of any psychiatric disorder have almost two times the risk of postpartum depression as do mothers without such history, according to a new study. Mette-Marie Zacher Kjeldsen, MSc, with the National Center for Register-based Research at Aarhus (Denmark) University, led the study, a meta-analysis that included 26 studies with … Read more

Omega-3 Fatty Acids Protective Against Depressive Episodes?

New research is suggesting that there are “meaningful” associations between higher dietary intake of omega-3 fatty acids and lower risk for depressive episodes. In a longitudinal study of more than 13,000 participants, consumption of omega-3 fatty acids (total and subtypes) was associated with a 2%-65% reduction in the risk for depressive episodes in patients with … Read more

Positive Phase 3 Results for Novel Schizophrenia Drug

The investigational agent xanomeline-trospium (KarXT, Karuna Therapeutics), which combines a muscarinic receptor agonist with an anticholinergic agent, helps improve psychosis symptoms, and is not associated with weight gain or sedation in adults with schizophrenia, new research shows. Top-line results from the phase 3 EMERGENT-2 trial showed a significantly greater reduction from baseline on Positive and … Read more