Impaired Vision an Overlooked Dementia Risk Factor

Impaired vision in older adults is an underrecognized and modifiable dementia risk factor, new research suggests. Investigators analyzed estimated population attributable fractions (PAFs) associated with dementia in more than 16,000 older adults. A PAF represents the number of dementia cases that could be prevented if a given risk factor were eliminated. Results showed the PAF … Read more

Does Metformin Blunt Diabetes Link to Brain Aging?

Researchers published the study covered in this summary on medRxiv.org as a preprint that has not yet been reviewed. Key Takeaways Type 2 diabetes appears to significantly accelerate normal brain aging. Metformin use does not appear to prevent neurocognitive decline. Why This Matters Although preliminary evidence links type 2 diabetes to neurologic and cognitive decline, … Read more

More Evidence COVID ‘Brain Fog’ Is Biologically Based

Patients with persistent cognitive impairment months after illness with mild COVID-19 have higher levels of inflammatory markers in their cerebrospinal fluid (CSF). Researchers found elevated levels of CSF immune activation and immunovascular markers in individuals with cognitive post-acute sequelae of SARS-CoV-2 infection (PASC). Patients whose cognitive symptoms developed during the acute phase of COVID-19 had … Read more

Executive Function Deficits a New Treatment Target for PTSD?

DENVER — Deficits in executive function are linked to with development of posttraumatic stress disorder (PTSD) symptoms and exacerbation of such symptoms over time, new research suggests. “To our knowledge, this study is the first to show that executive function deficits maintain PTS symptoms following trauma exposure,” investigators note in research presented here at the … Read more

Post-COVID Cognitive, EEG Changes Persist Up to 10 Months

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients who recover from COVID-19 show interrelated cognitive, EEG, and MRI abnormalities 2 months after hospital discharge — with some “disurbances” persisting as long as 10 months later, new research suggests. In a cohort of patients admitted to the emergency department … Read more

First ‘Before-and-After’ COVID Brain Imaging Study Shows Changes

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Even mild cases of COVID-19 are associated with brain changes including decreased gray matter, an overall reduction in brain volume, and cognitive decline, a new imaging study shows. In the first study to use magnetic resonance brain imaging, before and after … Read more