Time to Test Effects of CBD in Cardiovascular Disease?

Well-designed clinical trials to test the safety and efficacy of cannabidiol (CBD) for cardiovascular disease are needed, based on evidence from preclinical studies showing that it has anti-inflammatory effects, a new report suggests. The systematic review of nine preclinical studies found reproducible positive adverse outcomes in vivo models with CBD. Mechanisms for the findings included … Read more

AHA Guidance on Infective Endocarditis With Injection Drug Use

Prompted by the “unprecedented” increase in the occurrence of infective endocarditis cases among people who inject drug, the American Heart Association (AHA) has issued a scientific statement devoted to this challenging patient population. The statement provides a more in-depth focus on the management of infective endocarditis (IE) among this unique population than what has been … Read more

LAIAs More Effective Than Oral Antipsychotics for Schizophrenia

For patients with schizophrenia, long-acting injectable antipsychotics (LAIAs) are associated with a lower risk than oral antipsychotics (OAs) for disease relapse and hospitalization ― and they carry no increased risk for adverse events, new research shows. Investigators analyzed data for more than 70,000 patients with schizophrenia and found that, compared with OAs, LAIAs were associated … Read more

Social Isolation, Loneliness Tied to Death, MI, Stroke: AHA

People who are socially isolated or lonely have an increased risk for myocardial infarction (MI), stroke, and death, independent of other factors, the American Heart Association (AHA) concludes in a new scientific statement. Crystal Wiley Céné “Over four decades of research has clearly demonstrated that social isolation and loneliness are both associated with adverse health … Read more

Metabolic Syndrome Raises Dementia Risk in Under-60s

The more components of metabolic syndrome a person has in midlife seems to raise their risk of dementia, although that relationship seems to go away after age 70, a post hoc analysis of data from a major European cohort study has found. A team of European researchers reported online in the journal Diabetes Care that … Read more

Primary Hyperparathyroidism Raises Fracture, CV Risk

Dr Mattias Lorentzon Patients with untreated primary hyperparathyroidism show significant increases in the risk of hip fracture, cardiovascular events, and mortality, however, the risk is reduced when treated with parathyroidectomy, results from a large sample of patients in Sweden show. “Our results indicate that the risk of these severe outcomes is lower after surgery than … Read more

Patients’ Mental Health a Focus for Primary Care Clinicians

Is it possible to separate the heart from the mind? The answer is “no,” according to specialists who met at the 39th Congress of the State of Rio de Janeiro Society of Cardiology (SOCERJ), an event held virtually in May. During a conference on mental health, physicians and psychologists recalled that long-term data have suggested … Read more

Antipsychotic Tied to Weight Gain, Higher Cholesterol

Increases in use of the antipsychotic risperidone (Risperdal) are associated with small dose-related increases in both weight and blood cholesterol levels, new research suggests. Investigators analyzed 1-year data for more than 400 patients who were taking risperidone and/or its metabolite paliperidone (Invega). Results showed increments of 1 mg of risperidone-equivalent doses were associated with an … Read more

Running to the Top: Exercise and Mental Health

An apple a day keeps the doctor away! We’ve probably been given this advice or know of others who have been given this advice time and time again… to eat healthier, and more important, to exercise. While exercise is not necessarily the cure-all for the world’s infections and diseases, it plays an important role in … Read more

Exercise Provides Twice the CV Benefit in Anxiety, Depression

Meeting guideline-recommended exercise targets is associated with a reduced risk of cardiovascular disease (CVD) in everyone, but the benefits may be particularly clear for people with anxiety and depression, a new analysis suggests. In a study of more than 50,000 adult patients with or without CVD or risk factors who were followed for a median … Read more