Long-term Antidepressant Use Tied to Increased CVD, Mortality Risk

Long-term antidepressant use is tied to an increased risk of adverse outcomes, including cardiovascular disease (CVD), cerebrovascular disease (CV), coronary heart disease (CHD), and all-cause mortality, new research suggests. Investigators drew on 10-year data from the UK Biobank on over 220,000 adults and compared the risk of developing adverse health outcomes among those taking antidepressants … Read more

Folic Acid Tied to a Reduction in Suicide Attempts

Prescription folic acid, a synthetic form of vitamin B9, may provide a safe and effective approach for decreasing suicidal ideation, new research suggests. After adjusting for multiple factors, results from a large pharmaco-epidemiological study showed taking folic acid was associated with a 44% reduction in suicide events. Dr Robert Gibbons “These results are really putting … Read more

Deep Brain Stimulation Effective for OCD, but Barriers Persist

Deep brain stimulation (DBS) is safe and effective for individuals with severe obsessive-compulsive disorder (OCD) that has been resistant to conventional therapy, a meta-analytic review confirms. “DBS is a viable option for treatment-resistant OCD that can be expected to produce a significant clinical benefit in about 2 out of 3 cases,” study investigator Wayne Goodman, … Read more

MDD Tied to Childhood Trauma Is Treatable

Despite a higher symptom burden, patients with major depressive disorder (MDD) and a history of childhood trauma (CT) can achieve significant recovery following treatment with a combination of pharmacotherapy and psychotherapy, new research suggests. Results from a meta-analysis of 29 studies from 1966 to 2019, which included almost 7000 adults with MDD, showed that more … Read more

Timing of Food Intake a Strategy for Treating Mood Disorders?

Shift workers who confine their eating to the daytime may experience fewer mood symptoms compared to those who eat both day and night, new research suggests. Investigators at Brigham and Women’s Hospital, Boston, Massachusetts, created a simulated nightwork schedule for 19 individuals in a laboratory setting. Participants then engaged in two different meal timing models … Read more

Toward a New Open-Door Model for Psychiatric Wards

If isolated, patients with mental disorders may end up having higher levels of social impairment. This has led several hospitals in Spain to set up open-door departments that are more accessible. The purpose of the open-door model is to help remove the stigma from individuals who need to be admitted to a psychiatric ward because … Read more

Brodalumab Suicide Risk Similar to Other Biologics, Study Finds

An analysis of postmarketing suicide data shows that the risk of suicide associated with brodalumab use is similar to that of other biologics prescribed for psoriasis. The Food and Drug Administration approved brodalumab (Siliq) in 2017 for treatment of moderate to severe plaque psoriasis with a boxed warning for suicidal ideation and behavior and an … Read more

Urgent Need for Research Into Psychedelic Tx for Older Adults

Older age is associated with many health conditions that could potentially benefit from psychedelic-assisted therapy, yet very few older adults have been included in clinical trials of psychedelics, new research shows. “Geriatric psychiatrists and others caring for older adults are interested in how much is known about psychedelic use in older adults,” study investigator C. … Read more

Is Corporate Telepsychiatry the Solution to Access to Care Problems?

When Sue W’s mother died in 2018, she struggled terribly. She was already seeing a psychotherapist and was taking duloxetine, prescribed by her primary care physician. But her grief was profound, and her depression became paralyzing. She needed to see a psychiatrist, and there were many available in or near her hometown, a Connecticut suburb … Read more

Why Do We Want to Tough It Out?

We physicians come to the noble profession to heal and help others. Over years of education and training, we learn to be compassionate and empathic not only toward our patients but also to people around us. Patients’ safety and care become our priority. And at some point, we forget about ourselves. We forget that we … Read more