Lipid Signature May Flag Schizophrenia

A specific lipid profile can identify patients with schizophrenia, possibly paving the way for the development of the first clinically useful diagnostic test for a severe psychiatric illness, new research suggests. Although such a test remains a long way off, the investigators said, the identification of the unique lipid signature is a critical first step. … Read more

Psychiatric Illnesses Share Common Brain Network

A network of neural connections is linked to six psychiatric disorders: schizophrenia, bipolar disorder (BD), depression, addiction, obsessive-compulsive disorder (OCD), and anxiety, new research shows. Investigators used coordinate and lesion network mapping to assess whether there was a shared brain network common to multiple psychiatric disorders. In a meta-analysis of almost 200 studies encompassing more … Read more

Depression Guidelines Fall Short in Characterizing Withdrawal

Current depression guidelines offer incomplete guidance for clinicians to identify antidepressant withdrawal, based on data from a review of 21 guidelines. Previous research suggests that approximately half of patients who discontinue or decrease dosage of antidepressants experience withdrawal symptoms, wrote Anders Sørensen, MD, of Copenhagen University Hospital, and colleagues. These symptoms are diverse and may … Read more

Anxiety Sensitivity Fuels Depression in DID

Higher levels of anxiety sensitivity were associated with more severe depression in adults with dissociative identity disorder, based on data from 21 individuals. Xi Pan, LICSW, MPA Anxiety sensitivity refers to fear of the signs and symptoms of anxiety based on the individual’s belief that the signs of anxiety will have harmful consequences, wrote Xi … Read more

Concern Grows Over ‘Medical Aid in Dying for Mental Illness’ Law

Amid growing concern among the public, psychiatrists, and other mental health professionals, the Canadian government is seeking to delay the legalization of its proposed medical assistance in dying (MAID) for mental illness law that is slated to pass on March 17. Canada already has the largest number of deaths by MAID of any nation, with … Read more

Music Tied to Improved Mood, Less Stress During Times of Crisis

Regularly listening to music during times of crisis can significantly improve mood and relieve stress, new research suggests. In a cohort study of more than 700 adults, music listening during the COVID-19 pandemic was “prospectively associated” with lower momentary stress levels, better mood levels, and calmness–music perceived as “happy” was especially beneficial. The study corroborates … Read more

Childhood Behavior Linked to Poor Economic Results in Adulthood

Children with chronically elevated externalizing symptoms, such as behavioral problems, or internalizing symptoms, such as mental health concerns, have an increased risk for poor economic and social outcomes in adulthood, data from a new study suggests. Children with comorbid externalizing and internalizing symptoms were especially vulnerable to long-term economic and social exclusion. Dr. Massimiliano Orri … Read more

ADHD Exacts Higher Mental Health Toll vs Autism in Adults

Attention-deficit hyperactivity disorder (ADHD) is more predictive of poor mental health in adults than autism spectrum disorder (ASD), new research suggests. In a trait-based analysis of more than 500 adults, researchers found that ADHD traits trumped ASD traits in predicting internalizing problems. “Further research is now needed to delve deeper into understanding exactly why ADHD … Read more

Brain Differences Suggest Therapeutic Targets in Takotsubo

A new study has identified differences in the brain present in patients with the cardiac disorder Takotsubo syndrome vs control scans, which may lead to new therapeutic targets. Takotsubo syndrome is an acute heart failure cardiomyopathy mimicking an acute myocardial infarction (MI) in its presentation, but on investigation, no obstructive coronary disease is present. The … Read more

Assessment in Primary Care Pediatrics

The assessment and diagnosis of bipolar disorder in youth has a complicated and controversial history. I recall from my child and adolescent fellowship training that there was a thinly veiled faculty argument about the diagnosis itself with strong opinions on each side. To revisit this quandary, I reviewed the most up-to-date literature and outlined a … Read more