The Hunt for N-Acetylcysteine: Medicine or Dietary Supplement?

Medicine or dietary supplement? N-acetylcysteine ​​(NAC) is marketed as both and in 2021, the supplement abruptly became difficult to find, causing distress to people who had been using it for a variety of conditions. The story behind its disappearance is one of a cat-and-mouse chase between manufacturers, advocacy agencies, and the Food and Drug Administration. … Read more

Telehealth Benefits for OUD Prompts Call for Permanent Adoption

A new study provides strong support for permanent adoption of expanded telehealth services and flexible prescribing of medications for opioid use disorder (OUD), experts say. Results showed that expanded access to telehealth services, authorized during the COVID-19 pandemic, led to more Medicare beneficiaries with OUD entering treatment and staying in treatment, as well as to … Read more

I Missed It: Coping With Medical Error

Thursday Night It was 9 o’clock at night when my phone rang. I didn’t recognize the number but decided to answer it anyway. It was my doctor. “Chase, I got your labs back and you have a critically low level. I spoke with someone at the hospital, I think I know what is happening, but … Read more

Stable, Long-term Opioid Therapy Safer Than Tapering?

Discontinuing Stable, Long-TERM OPIOIID Therapy May Not BE NECESAY FOR PATIENTS who show no Signs of Misuse ― and IT COUL Even Be Safer Than Tapering Or Aburt Discontinism, New Research Suggests. Investigators Analyzed Data for Almost 200,000 Patients who did not have signs of OPIOOID USE DISEORDER (Oud) and Were Receiving Opioid Treatment. The … Read more

They Call It ‘Tranq,’ and It’s Making Street Drugs More Dangerous

Approaching a van that distributes supplies for safer drug use in Greenfield, Massachusetts, a man named Kyle noticed an alert about xylazine. “Xylazine?” he asked, sounding out the unfamiliar word. “Tell me more.” Tapestry Health Systems nurse Katy Robbins hands bottles of water to Kyle as he visits the harm reduction mobile unit in Greenfield, … Read more

‘Shocking’ and Persistent Gap in Treatment for Opioid Addiction

The vast majority of Americans with opioid use disorder (OUD) do not potentially receive lifesaving medications. Drugs such as methadone, buprenorphine, and extended-release naltrexone have been shown to reduce opioid overdoses by more than 50%. Yet a new analysis shows that only about 1 in 10 people living with OUD receive these medications. Dr Noa … Read more

First US Sanctioned Safe Injection Sites Curb Overdose Risk

Overdose prevention centers (OPCs) decrease overdose risk and curb public use of illicit drugs, according to early data from the first two federally sanctioned centers in the United States — both in New York City (NYC). In 2020, 2062 people died of a drug overdose in NYC — the deadliest year on record for the … Read more

Antidepressants May Curb Opioid Overdose

Patients with a history of depression who are also being treated with opioid analgesics have a lower risk for overdose and self-harm after taking antidepressants, new research suggests. Investigators analyzed insurance claims for more than 200,000 adults with a history of depression. Of these, 8200 experienced adverse events (AEs) during the year after initiation of … Read more

Homelessness Overrepresented in Canadian Overdose Deaths

People experiencing homelessness were overrepresented among those who died of substance-related acute toxicity in Canada in 2016 and 2017, according to a new report. Among those who were homeless at the time of their death, at least 1 in 10 were released from a correctional or healthcare institution in the month before their death. In … Read more

Judge Rules in Favor of 3 Drug Distributors in Opioid Lawsuit

A federal judge ruled in favor of three major US drug distributors on Monday in a landmark opioid case, which accused the companies of causing a health crisis by distributing 81 million pills in 8 years in certain parts of West Virginia. Nearly a year after closing arguments, US District Judge David Faber gave the … Read more