Depression Guidelines Fall Short in Characterizing Withdrawal

Current depression guidelines offer incomplete guidance for clinicians to identify antidepressant withdrawal, based on data from a review of 21 guidelines. Previous research suggests that approximately half of patients who discontinue or decrease dosage of antidepressants experience withdrawal symptoms, wrote Anders Sørensen, MD, of Copenhagen University Hospital, and colleagues. These symptoms are diverse and may … Read more

Emotional Eating Tied to Risk for Diastolic Dysfunction

Eating in response to stress — known as emotional eating — was significantly associated with several markers of long-term cardiovascular damage, based on data from 1,109 individuals. “We know diet plays a huge role in cardiovascular disease, but we’ve focused a lot of work on what you eat, not on what makes you eat” — … Read more

More Evidence Suicidal Thoughts, Behaviors Are Genetically Based

A genome-wide association study (GWAS) of suicidal thoughts and behaviors (SITB) has identified significant cross-ancestry risk loci. The findings provide further evidence of a genetic basis for SITB. Dr. Allison Ashley-Koch “It’s really important for us to continue to study the genetic risk factors for suicidal behaviors so we can really understand the biology and … Read more

Greater Handgrip Strength Tied to Lower Risk for Depression

Weak handgrip in older adults is linked to a higher risk for depression — while a stronger handgrip may have protective benefits, new research suggests. In a study of more than 115,000 adults, there was a significant association between a stronger handgrip, up to 40 kg in men and 27 kg in women, and lower … Read more

Climate Change Has Consequences for Mental Health

The topic of discussion at the United Nations (UN) Climate Change Conference in Sharm El-Sheikh, Egypt, was how the consequences of climate change may be mitigated. To date, the discussion has been focused on the environment, living conditions, and people’s physical health. However, the effects on the mind are no less dramatic, emphasizing the German … Read more

‘Striking’ Rate of Suicidal Thoughts in Teens With Epilepsy

NASHVILLE, Tennessee ― About 21% of teens are newly diagnosed with epilepsy experience suicidal ideation, and the percentage jumps to 31% within 3 years, new research reveals. Dr Hadley Greenwood “We hope these results inspire epileptologists and neurologists to both recognize and screen for suicide ideation and behaviors in their adolescent patients,” study investigator Hadley … Read more

Novel Intervention Relieves Depression in MS Patients

An internet-based cognitive-behavioral therapy (iCBT) program specifically designed for patients with multiple sclerosis (MS) significantly reduced depressive symptoms compared to usual treatment, new research shows. Participants in the randomized controlled trial who received iCBT either benefits alone or in combination with weekly emails from therapists reported that persisted up to a year after therapy. Although … Read more

Major Depression Treatments Boost Brain Connectivity

VIENNA — Inpatient treatment for major depressive disorder (MDD) can lead to brain connectivity increases that are associated with degree of symptom improvement, new research suggests. In a “repeat” MRI study, adult participants with MDD had significantly lower brain connectivity compared with their healthy peers at baseline — but showed significant improvement at the 6-week … Read more

Nicotine Blocks Estrogen Production in Women’s Brains

The production of estrogen in the thalamus appears to be curtailed by just one dose of nicotine, equivalent to that in a cigarette, reveals a whole brain analysis of healthy women in the first study of its kind. The findings were presented at the 35th European College of Neuropsychopharmacology (ECNP) Congress. The researchers performed both … Read more

‘U-Shaped’ Relationship Between Bipolar Risk and Parental Age

VIENNA — Individuals born to younger or older parents are at increased risk of developing bipolar disorder, new research suggests. Results from a meta-analysis of more than 210,000 patients with bipolar disorder and over 13 million healthy individuals showed that children of mothers younger than 20 years had a 23% increased risk for bipolar disorder … Read more