Mental Disorders Up in Youth With Prenatal Cannabis Exposure

Exposure to cannabis in the womb may leave children at risk for psychiatric disorders and problematic substance abuse, particularly as they enter peak periods of vulnerability in late adolescence, new research shows. In a study published September 12 in JAMA Pediatrics, the investigators say the results should prompt further caution against the use of cannabis … Read more

Time to Test Effects of CBD in Cardiovascular Disease?

Well-designed clinical trials to test the safety and efficacy of cannabidiol (CBD) for cardiovascular disease are needed, based on evidence from preclinical studies showing that it has anti-inflammatory effects, a new report suggests. The systematic review of nine preclinical studies found reproducible positive adverse outcomes in vivo models with CBD. Mechanisms for the findings included … Read more

Cannabis for Pain Linked to Slight Risk for Arrhythmia

Patients who received a first prescription for medicinal cannabis for chronic pain were more likely to have new onset of arrhythmia — bradyarrhythmia, tachyarrhythmia, or a conduction disorder — within 6 months than were similar nonusers, in a new case-control study. There were no between-group differences in the incidence of heart failure or acute coronary … Read more

Local Public Health Efforts in Schools May Not Work

Efforts to prevent and curb substance use in schools through public health engagement (PHE) appear to be effective where use of cigarettes and cannabis is high but had the opposite impact in where use of alcohol and cannabis is low, according to a cross-sectional study published in the Canadian Journal of Public Health. The study … Read more

Potent Cannabis Linked to More Worldwide Addiction

Cannabis potency has increased worldwide in recent decades and is linked with more people becoming addicted to marijuana, according to a new study published in Lancet Psychiatry. People who use higher concentrations of tetrahydrocannabinol, or THC, are more likely to have addiction and mental health problems, the study authors found. For research, scientists have established … Read more

Study Sees Surge in Use of Medical Cannabis

In 2020 nearly 3 million people in the United States sought out medical cannabis, in marijuana or other forms, more than four times the number who did so in 2016, a new study has found. Much of the increase involved people seeking medical cannabis for chronic pain, which remains the leading reason Americans say they … Read more

Cannabis on Par With Opioids for Pain Relief, Study Suggests

Cannabis-based products may control chronic pain as effectively as opioids, but adverse effects are common, and long-term safety remains unknown, according to a new study. Several other systematic reviews have recently evaluated cannabinoids for treating chronic pain, but the new study’s methodology was “distinct” in “important ways,” leading to “conclusions that differ from other reviews,” … Read more

Cannabinoids in Medicine: Limitless Hope or Hype?

What is the role of cannabinoids as an intoxicant and in medical applications today? This was the question addressed by Dieter Braus, MD, psychiatrist and neurologist at Vitos Clinic Rheingau in Eltville, Germany, at the DGIM Congress 2022. Dampening the Dopamine System Regardless of the type of substance-dependent addiction — whether alcohol, opiates, nicotine, or … Read more

Long-Term Cannabis Use Linked to Dementia Risk Factors

Long-term cannabis use is linked to hippocampal atrophy and poorer cognitive function in midlife — known risk factors for dementia. A large prospective, longitudinal study showed long-term cannabis users had an intelligence quotient (IQ) decline from age 18 to midlife (mean 5.5 IQ points), poorer learning and processing speed compared to childhood, and self-reported memory … Read more

Cannabis Exposure in Pregnancy Linked With Childhood Obesity

There is a link between cannabis exposure in during pregnancy and higher fasting glucose levels and adiposity in the offspring in early childhood, a new study suggests. Research looking at the effect of prenatal exposure to cannabis on offspring is growing. It is known to affect childhood cognition and behavior; However, there is little work … Read more