Time to Test Effects of CBD in Cardiovascular Disease?

Well-designed clinical trials to test the safety and efficacy of cannabidiol (CBD) for cardiovascular disease are needed, based on evidence from preclinical studies showing that it has anti-inflammatory effects, a new report suggests. The systematic review of nine preclinical studies found reproducible positive adverse outcomes in vivo models with CBD. Mechanisms for the findings included … Read more

Metabolic Syndrome Raises Dementia Risk in Under-60s

The more components of metabolic syndrome a person has in midlife seems to raise their risk of dementia, although that relationship seems to go away after age 70, a post hoc analysis of data from a major European cohort study has found. A team of European researchers reported online in the journal Diabetes Care that … Read more

Liver Disease a New Dementia Risk Factor?

Nonalcoholic fatty liver disease (NAFLD) is linked to an increased dementia risk, with an even greater risk in the setting of comorbid heart disease or history of stroke, new research shows. Investigators analyzed data for almost 3000 older individuals diagnosed with NAFLD and compared them with a large group of matched peers without NAFLD. At … Read more

Early Metformin Minimizes Antipsychotic-Induced Weight Gain

MAR DEL PLATA, Argentina ― Psychiatrists should prescribe metformin early to patients who experience rapid weight gain after they begin taking antipsychotic drugs, according to a new evidence-based Irish guideline for the management of this common complication in adults with psychoses who are taking medications. The document was discussed during one of the sessions of … Read more

What Role Does Loneliness Play in Diabetes Risk?

Our individual and collective COVID experiences, now about 2 years old and counting, will undoubtedly register as one of those global events that transformed lives and outlooks. My grandparents talked about the Depression, my parents World War II, and contemporary physicians and most contemporary Americans probably will convey memories of 9/11 and COVID to our … Read more