Metabolic Syndrome Raises Dementia Risk in Under-60s

The more components of metabolic syndrome a person has in midlife seems to raise their risk of dementia, although that relationship seems to go away after age 70, a post hoc analysis of data from a major European cohort study has found. A team of European researchers reported online in the journal Diabetes Care that … Read more

Genetic Testing for Best Antidepressant Accurate, Cost-Effective

Genetic testing to determine the best antidepressant for patients with major depressive disorder (MDD) has the potential to lead to an optimal drug choice on the first try and reduce healthcare costs, new research suggests. CYP2D6 and CYP2C19, from the cytochrome P450 family, are involved in the metabolism and elimination of various molecules, including medications. … Read more

Antipsychotic Tied to Weight Gain, Higher Cholesterol

Increases in use of the antipsychotic risperidone (Risperdal) are associated with small dose-related increases in both weight and blood cholesterol levels, new research suggests. Investigators analyzed 1-year data for more than 400 patients who were taking risperidone and/or its metabolite paliperidone (Invega). Results showed increments of 1 mg of risperidone-equivalent doses were associated with an … Read more

Cannabis Exposure in Pregnancy Linked With Childhood Obesity

There is a link between cannabis exposure in during pregnancy and higher fasting glucose levels and adiposity in the offspring in early childhood, a new study suggests. Research looking at the effect of prenatal exposure to cannabis on offspring is growing. It is known to affect childhood cognition and behavior; However, there is little work … Read more