Greater Handgrip Strength Tied to Lower Risk for Depression

Weak handgrip in older adults is linked to a higher risk for depression — while a stronger handgrip may have protective benefits, new research suggests. In a study of more than 115,000 adults, there was a significant association between a stronger handgrip, up to 40 kg in men and 27 kg in women, and lower … Read more

High Neuro Drug Costs Exclude Most From Cutting-Edge Tx

Because of high out-of-pocket costs of new-to-market neurologic drugs that are of similar benefit as older agents, only a small percentage of patients with neurologic disorders have access to these cutting-edge medications, new research shows. “Our study of people with neurologic conditions found fewer than 20% were being treated with new medications,” study author Brian … Read more

The Hidden Dangers of Pathologizing Grief

The Weekend That I graduated from law school, my mother told me that she had amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, a neurological disease for which there is currently no cure. As I recalled in a recent essay, I spent the following year watching as her muscles atrophied until she … Read more

Brain Implant Allows Fully Paralyzed Patient to Communicate

An experimental brain-computer interface has allowed a man with amyotrophic lateral sclerosis (ALS) who was unable to speak or move to communicate. Using a commercially available implant and newly designed software, the patient, who was in the advanced stages of Lou Gehrig’s disease and unable to move his eyes, was able to interact with researchers … Read more

Promising Disease Markers in Amyotrophic Lateral Sclerosis

The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Seven nerve excitability indices distinguish patients with amyotrophic lateral sclerosis (ALS) from healthy controls. Four indices may be biomarkers of early stage ALS. Why This Matters There is no diagnostic test for ALS, … Read more