Ketamine Linked to Reduced Suicidal Thoughts, Depression, Anxiety

Ketamine infusions can help reduce symptoms of suicidal ideation, depression, and anxiety in patients with treatment-resistant depression (TRD), new research suggests. Results from a retrospective chart review analysis, which included more than 400 participants with TRD, illustrated that ketamine is a safe and rapid treatment in a real-world patient population, lead author Patrick A. Oliver, … Read more

Subtle Visual Dysfunctions Often Precede Early-Stage Psychosis

Subtle subjective visual dysfunctions (VisDys) are common and are associated with poorer outcomes of patients with schizophrenia and recent-onset psychosis or who are at clinical high risk (CHR) for psychosis, new research suggests. A multinational group of investigators found that said Vis-more often by patients with recent onset psychosis and CHR than by those with … Read more

Chemokine Expression Predicts MDD Severity

Adults with major depressive disorder (MDD) had significantly reduced expression of chemokine receptor 4 on blood T lymphocytes, which predicted disease severity in combination with polygenic risk scores in a study of 54 individuals. Chemokines and their receptors “influence neuroendocrine signaling, neurotransmission, and interaction between neurons and microglia and have therefore been suggested to be … Read more

Faster Response to IV vs Intranasal Ketamine in Depression

NEW ORLEANS – New research reveals that patients with treatment-resistant depression who were treated with repeated intravenous differences ketamine show no significant in achieving response or remission, compared with those receiving the intranasal formulation of the drug, esketamine – although fewer treatments appear necessary with the intravenous formulation. Dr Balwinder Singh “This is one of … Read more