Inhaled, Systemic Steroids Linked to Changes in Brain Structure

New research links the use of glucocorticoids with changes in white matter microstructure — which may explain the development of anxiety, depression, and other neuropsychiatric side effects related to these drugs, investigators say. Results from a cross-sectional study showed that use of both systemic and inhaled glucocorticoids was associated with widespread reductions in fractional anisotropy … Read more

Death Risk Spikes With New Onset-Depression After RA Diagnosis

The development of depression after a rheumatoid arthritis diagnosis increased the risk for death “more than sixfold” when compared with having no depression at diagnosis, according to Danish researchers. Cumulative mortality at 10 years was approximately 37% in patients with comorbid RA and depression versus around 13.5% of RA patients with no depression, Jens Kristian … Read more

Maternal Autoimmune Diseases Up Risk of Mental Illness in Children

Mental disorders were significantly more likely in children whose mothers had one of five common autoimmune diseases, a new study found. Previous research has linked both maternal and paternal autoimmune diseases and specific mental disorders, such as attention-deficit/hyperactivity disorder (ADHD), but most of these studies focused on specific conditions in relatively small populations. The new … Read more