A Little-Known Option for Depression

Standard therapies for depression are antidepressants and psychotherapy. In particularly severe cases, electroconvulsive therapy (ECT) or vagus nerve stimulation (VNS) may also be indicated. VNS is an approved, effective, well-tolerated, long-term therapy for chronic and therapy-resistant depression, write Christine Reif-Leonhardt, MD, and her team of researchers from the University Hospital Frankfurt am Main, Germany, in … Read more

Study Provides New Data on Isotretinoin and Psychiatric Effects

The use of isotretinoin to treat acne was not associated with an increase in adverse neuropsychiatric outcomes, compared with the use of oral antibiotics, in a large retrospective cohort study published in the British Journal of Dermatology. Although severe neuropsychiatric effects associated with isotretinoin therapy in patients with acne have been reported, “the evidence base…is … Read more

Antipsychotic Switch Rates Suggest ‘Suboptimal’ FEP Prescribing

High rates of antipsychotic switching in first episode psychosis (FEP) suggests first-line prescribing is less than optimal and does not follow recent clinical guidance. In a large-scale, real-world analysis of researchers UK prescribing patterns, found more than two thirds of patients who received antipsychotics for FEP switched medication and almost half switched drugs three times. … Read more

Methylphenidate Is Overprescribed to Children in France

The prevalence of attention-deficit/hyperactivity disorder (ADHD) is difficult to evaluate, and the diagnosis is based primarily on clinical criteria. In 2008, a French study estimated the prevalence to be between 3.5% and 5.6%, but the study’s design was questionable. Treatment of this disorder consists first and foremost in educational, social, and psychotherapeutic management. Only if … Read more

Debate Heats Up on How Best to Treat Gender-Questioning Kids

The past week has seen heated debate about the complex issue of how to best treat children with gender dysphoria, with further developments in a number of US states as well as in Sweden and France. In the United States, more states have moved to prevent the use of any medical treatment, such as puberty … Read more