Naloxone May Fail for Overdoses Tainted With ‘Tranq,’ FDA Warns

The US Food and Drug Administration (FDA) is alerting healthcare professionals about the special management required for opioid overdoses tainted with xylazine, an animal tranquilizer known on the street as tranq, tranq dope, sleep-cut, Philly dope, and zombie drug. The tranquilizer is often combined with fentanyl or heroin, or occasionally with a stimulant, said the … Read more

Home-Based Transcranial Stimulation Succeeds for Major Depression

Home-based transcranial direct current stimulation with real-time supervision significantly improved clinical symptoms of major depressive disorder, based on data from 26 individuals. Major depressive disorder (MDD) remains a leading cause of disability and a significant predictor of suicide worldwide, Rachel D. Woodham, PhD, of the University of East London and colleagues wrote. Transcranial direct current … Read more

Home-Based Stimulation Linked to ‘Clear Improvement’ in Adult ADHD

Transcranial direct current stimulation (tDCS) using a home-based device can help improve attention in adults with attention-deficit/hyperactivity disorder (ADHD) who are not taking stimulants, new research suggests. Results from the sham-controlled trial also showed that the tDCS treatment was both safe and well tolerated. Overall, the findings suggest that the device could be a nondrug … Read more

Homelessness Overrepresented in Canadian Overdose Deaths

People experiencing homelessness were overrepresented among those who died of substance-related acute toxicity in Canada in 2016 and 2017, according to a new report. Among those who were homeless at the time of their death, at least 1 in 10 were released from a correctional or healthcare institution in the month before their death. In … Read more

The Struggle of Treating Executive Dysfunction

Maybe you know some of these patients: they may come late or not show up at all. They may have little to say and minimize their difficulties, often because they are ashamed of how much effort it takes to meet ordinary obligations. They may struggle to complete assignments, fail classes, or lose jobs. And being … Read more

Adherence to ADHD Meds May Lower Unemployment Risk

Adherence to medication for attention-deficit/hyperactivity disorder (ADHD) is linked to a significantly lower risk for illness, particularly among women, new research suggests. Investigators analyzed data for almost 13,000 working-age adults with ADHD and found ADHD medication use during the previous 2 years was associated with a 10% lower risk for long-term unemployment in the following … Read more