Exercise for Obese Children Can Increase Brain Function

In recent years, schools cut back on arts and physical education to make way for more instructional time. All that work and no play may be making Jack and Jill, well, dull. But new research shows that exercise can make the brain sharper. The study demonstrated that a prolonged regimen of aerobic and resistance exercises … Read more

Ketamine Linked to Reduced Suicidal Thoughts, Depression, Anxiety

Ketamine infusions can help reduce symptoms of suicidal ideation, depression, and anxiety in patients with treatment-resistant depression (TRD), new research suggests. Results from a retrospective chart review analysis, which included more than 400 participants with TRD, illustrated that ketamine is a safe and rapid treatment in a real-world patient population, lead author Patrick A. Oliver, … Read more

Anorexia Linked to Notable Shrinkage of Key Brain Structures

Patients with anorexia nervosa (AN) have not able shrinkage in key brain structures and these deficits are less severe in patients on the path to weight recovery, a new brain imaging study shows. The reductions of cortical thickness, subcortical volumes, and cortical surface area were “very pronounced in acutely underweight anorexia,” Stefan Ehrlich, MD, PhD, … Read more

Antipsychotic Tied to Weight Gain, Higher Cholesterol

Increases in use of the antipsychotic risperidone (Risperdal) are associated with small dose-related increases in both weight and blood cholesterol levels, new research suggests. Investigators analyzed 1-year data for more than 400 patients who were taking risperidone and/or its metabolite paliperidone (Invega). Results showed increments of 1 mg of risperidone-equivalent doses were associated with an … Read more

Early Metformin Minimizes Antipsychotic-Induced Weight Gain

MAR DEL PLATA, Argentina ― Psychiatrists should prescribe metformin early to patients who experience rapid weight gain after they begin taking antipsychotic drugs, according to a new evidence-based Irish guideline for the management of this common complication in adults with psychoses who are taking medications. The document was discussed during one of the sessions of … Read more

What You Need to Know

Eating disorders are among the most prevalent, disabling, and potentially fatal psychiatric illnesses, and the COVID-19 pandemic has exacerbated their burden, with a 15.3% increase in incidence in 2020 compared with previous years.1 This increase was almost difficult among adolescent girls with anorexia nervosa (AN), which is often insidious in onset and more difficult to … Read more

New Med for Severe Mental Illness Tied to Less Weight Gain

Olanzapine plus samidorphan (Lybalvi) vs olanzapine alone is associated with less weight gain while achieving similar clinical outcomes in patients with recent-onset severe mental illness, new research suggests. However, least one expert says the weight difference between the two drugs is of “questionable clinical benefit.” Last year, the US Food and Drug Administration (FDA) approved … Read more

First Guidelines for Managing Anorexia in Pregnancy

The first comprehensive guidelines to manage pregnant women with anorexia nervosa (AN) have been released. Pregnant women with AN are at greater risk of poor outcomes including stillbirth, underweight infant, or pre-term birth, yet there are no clear guidelines on the management of the condition. “Anorexia in pregnancy has been overlooked area of ​​clinical care … Read more

Jury Is Out on Universal Screening for Eating Disorders

There is insufficient evidence to weigh the balance of benefits and harms of screening for eating disorders in adolescents and adults, the US Preventive Services Task Force (USPSTF) says in their first-ever statement on the topic. Eating disorders (binge eating disorder, bulimia nervosa, and anorexia nervosa) can cause “serious harms to physical and psychosocial health … Read more