Teen’s Undisclosed Dieting May Precede Anorexia Nervosa

Adolescents later diagnosed with anorexia nervosa (AN) likely embark on the trajectory to AN with undisclosed dieting for weight loss at about age 14, a study of teens and parents found. In the interview-based study, both adolescents and their parents described a similar prediagnosis sequence of behavioral changes occurring over roughly 1 year to 18 … Read more

Intermittent Fasting Diet Trend Linked to Disordered Eating

Intermittent fasting (IF), defined as fasting for more than eight hours at a time, is a trend that is growing in popularity. Yet new research shows it may be linked to eating disorder (ED) behaviors. Researchers from the University of Toronto analyzed data from more than 2,700 adolescents and young adults from the Canadian Study … Read more

Menopause an Independent Risk Factor for Schizophrenia Relapse?

Menopause appears to be an independent risk factor for relapse in women with schizophrenia spectrum disorders (SSDs), new research suggests. Investigators studied a cohort of close to 62,000 people with SSDs, stratifying individuals by sex and age, and found that starting between the ages of 45 and 50 years — when the menopausal transition is … Read more

Exercise for Obese Children Can Increase Brain Function

In recent years, schools cut back on arts and physical education to make way for more instructional time. All that work and no play may be making Jack and Jill, well, dull. But new research shows that exercise can make the brain sharper. The study demonstrated that a prolonged regimen of aerobic and resistance exercises … Read more

Ketamine Linked to Reduced Suicidal Thoughts, Depression, Anxiety

Ketamine infusions can help reduce symptoms of suicidal ideation, depression, and anxiety in patients with treatment-resistant depression (TRD), new research suggests. Results from a retrospective chart review analysis, which included more than 400 participants with TRD, illustrated that ketamine is a safe and rapid treatment in a real-world patient population, lead author Patrick A. Oliver, … Read more

Anorexia Linked to Notable Shrinkage of Key Brain Structures

Patients with anorexia nervosa (AN) have not able shrinkage in key brain structures and these deficits are less severe in patients on the path to weight recovery, a new brain imaging study shows. The reductions of cortical thickness, subcortical volumes, and cortical surface area were “very pronounced in acutely underweight anorexia,” Stefan Ehrlich, MD, PhD, … Read more

Antipsychotic Tied to Weight Gain, Higher Cholesterol

Increases in use of the antipsychotic risperidone (Risperdal) are associated with small dose-related increases in both weight and blood cholesterol levels, new research suggests. Investigators analyzed 1-year data for more than 400 patients who were taking risperidone and/or its metabolite paliperidone (Invega). Results showed increments of 1 mg of risperidone-equivalent doses were associated with an … Read more

Early Metformin Minimizes Antipsychotic-Induced Weight Gain

MAR DEL PLATA, Argentina ― Psychiatrists should prescribe metformin early to patients who experience rapid weight gain after they begin taking antipsychotic drugs, according to a new evidence-based Irish guideline for the management of this common complication in adults with psychoses who are taking medications. The document was discussed during one of the sessions of … Read more

What You Need to Know

Eating disorders are among the most prevalent, disabling, and potentially fatal psychiatric illnesses, and the COVID-19 pandemic has exacerbated their burden, with a 15.3% increase in incidence in 2020 compared with previous years.1 This increase was almost difficult among adolescent girls with anorexia nervosa (AN), which is often insidious in onset and more difficult to … Read more

New Med for Severe Mental Illness Tied to Less Weight Gain

Olanzapine plus samidorphan (Lybalvi) vs olanzapine alone is associated with less weight gain while achieving similar clinical outcomes in patients with recent-onset severe mental illness, new research suggests. However, least one expert says the weight difference between the two drugs is of “questionable clinical benefit.” Last year, the US Food and Drug Administration (FDA) approved … Read more